The next trains to depart from Cheadle Hulme according to the timetable are listed below. Times are subject to change - please click on any destination to view live departure boards to check the exact running time.
| Destination | Platform | Departs |
| Crewe | 2 | 08:24 PM |
| Manchester | 1 | 08:24 PM |
| Manchester | 3 | 08:37 PM |
| Stoke | 4 | 09:02 PM |
| Crewe | 2 | 09:24 PM |
| Manchester | 1 | 09:24 PM |
| Manchester | 3 | 09:37 PM |
| Stoke | 4 | 10:02 PM |
| Crewe | 2 | 10:24 PM |
| Manchester | 1 | 10:24 PM |
| Stoke | 4 | 11:02 PM |
| Manchester | 3 | 11:05 PM |
| Crewe | 2 | 11:23 PM |
| Stoke | 4 | 11:27 PM |
| Manchester | 1 | 11:46 PM |
| Crewe | 2 | 11:54 PM |